Abstract: As an expression of a generalized connective tissue defect, mitral valve prolapse (MVP) is often combined with other dysplastic changes that manifest themselves as a set of phenotypic signs of the body. The aim of this study was to identify the frequency and clinical manifestations of mitral valve prolapse in children associated with phenotypic manifestations of connective tissue dysplasia. In the course of the work, not only clinical, but also instrumental methods were used to study 60 children with a verified diagnosis of mitral valve prolapse who are being treated in the department of cardiorheumatology of the Andijan regional Children's Multidisciplinary Medical Center. As a result of the work carried out, it was found that the high frequency of phenotypic manifestations of connective tissue dysplasia in children with MVP indicates that the diverse clinical symptoms are not limited only to the defeat of the cardiovascular system.
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