RESULTS OF FACTOR ANALYSIS OF THE MAIN CLINICAL SYMPTOMS IN CHILDREN WITH BRONCHIAL ASTHMA WITH OBESITY

Abstract

Abstract: There are a number of scientific publications indicating the presence of numerous pathogenetic connections between asthma and accompanying obesity. Purpose of the study: factor analysis of the main clinical symptoms in children with bronchial asthma and obesity. Material and methods: We conducted a retrospective analysis of medical histories of children who were treated at the Andijan City Children's Hospital, the Andijan Regional Multidisciplinary Central Clinic, and in the departments of pulmonology and allergology of the Russian Scientific and Practical Medical Center of Pediatrics in 2015-2019. In 2015-2019, 8919 children aged 0 to 18 years with bronchopulmonary pathology were admitted for treatment, of which 485 children were diagnosed with BA, which amounted to 5.4%, among them there were 293 boys and 192 girls. Each re-applying child was hospitalized 4 to 6 times a year. Results and discussions: Factor analysis showed that in children with asthma and OB, cough, wheezing in the chest and shortness of breath occurred in 126 (96.9%) and was 2.12 times (RR) higher than in the control group. the share of excess morbidity (attributable risk) due to the influence of the risk factor is 0.102, the proportion of cases of the disease from the studied risk factor (etiological share) is 52.9%, the odds ratio in the group of BA with OB was 4.85 times higher than in the group with BA. Conclusions: Factor analysis of the main clinical symptoms encountered in the examined children with BA and OB showed that weakness, sweating, shortness of breath, lethargy, asthma attacks, wet cough and perioral wheezing are the main ones.