A NEW APPROACH TO THE TREATMENT OF RESPIRATORY DISEASES IN FREQUENTLY ILL CHILDREN

FULL TEXT:

Abstract

The article presents the indicators of immunoglobulins and staphylococcal antitoxin in the combined use of Broncho-munal and Sodium Nucleinate in frequently ill children in the treatment of respiratory diseases. The indicators of three classes of immunoglobulins (A, M, G) and staphylococcal antitoxin were studied in 146 frequently ill children from 1 to 6 years hospitalized in the department of pulmonology of the GDB No. 1 of Samarkand. Of these, 46 were treated with the traditional method (T), 50 with the traditional method using Broncho - munal (TB) and 50 with the traditional method using Broncho-munal and the adjuvant Sodium Nucleinate (TBN). The studies were conducted before treatment (146) and in dynamics before discharge from the hospital (146). The positive effect of the developed treatment method was manifested in the disappearance of signs of intoxication and relief of clinical symptoms in a short time, an increase in the indicators of nonspecific and specific factors with the formation of antitoxic and antibacterial immunity in the inductive and productive phase.

About the Authors

List of references

Muratkhodzhayeva A.V., Dauksh I.A., Khakimova U.R., Aliev A.L., Mirkhalikova D.I. The use of immunomodulatory therapy in the complex treatment of frequently ill children. Pediatrics 2014:109-111.

Shamsiev F.M., Khaidarova M.M., Mavlyanova S.S. Bronchitis in children (etiology, pathogenesis, clinic, diagnosis and treatment). Tashkent 2013:23–7.

Takhirova R.N. The importance of socio-biological factors in the formation of respiratory failure, complicated pneumonia in young children. Pediatrics 2015:19–20.

Buc M, Dzurilla M, Vrlik M, Bucova M. Immunopathogenesis of bronchial asthma. Arch Immunol Ther Exp (Warsz) 2009;57:331–44. https://doi.org/10.1007/s00005-009-0039-4.

Sirojiddinova X.N., Usmanova M.F., Ortikboyeva N.T., Tuxtayeva M.M. Immunological dynamics of recurrent respiratory infections in frequently sick children on the background of immunocorrective therapy. IJIEMR Transactions 2021;10:131–4.

Tukhtaeva M.M., Usmanova M.F., Omonova G.Z., Ochilova B.S. Psychomotor changes in hypoxic lesions of the central nervous system in newborns. Eurasian journal of academic research 2021;1:271–5.

Shamsiev F.M., Karimova N.I. Features of the criteria for predicting bronchial asthma in children. Pediatrics 2016:118–20.

Nuriddinovna SK, Mustafayevna NS, Tursunbayevna ON. Intrauterine infection as a developmental factor perinatal pathology. 1 2021;2:107–11. https://doi.org/10.47494/cajmns.v2i1.85.

Jesenak M., Ciljakova M.,Rennerova Z. et al. Recurrent Respiratory infections in Children – Definition, Diagnostic Approach, Treatment and Prevention. In: infectious Diseases, «Bronchitis». I Martin-Loeches ed 2011:10.

Tukhtaeva M.M., Abduxalik-Zade G.A., Burxonova D.B., Mirkomilova G.M. Clinic - anamnestic characteristic of hypoxic-ischemic encephalopathy in newborns. Eurasian journal of academic research 2021;1:261–5.

Khaitov R.M., Pinegin B.V. Immunomodulators: mechanism of action and clinical application. Immunology 2003:196–203.

Slatter MA, Gennery AR. Clinical immunology review series: an approach to the patient with recurrent infections in childhood. Clin Exp Immunol 2008;152:389–96. https://doi.org/10.1111/j.1365-2249.2008.03641.x.

Grishchenko T.P., Khvalov A.N. Non-drug correction of the respiratory tract in frequently ill children. Bulletin of otorhinolaryngology 2016:59–62.

Nikolaeva N.V., Bolotova N.V., Zotova Yu.A., Vladimirova E.V. The role of dynamic magnetic therapy in the rehabilitation of frequently ill children. Педиатрия 2008;87:56–61.

Nuriddinova S, Kizi I, Mustafayevna N, Tursunbayevna O, Dilshodbekovna A. Metabolic Changes Following Post-Hypoxic Complications in Newborns. International Journal of Current Research and Review 2020;12:173–7. https://doi.org/10.31782/IJCRR.2020.122229.

How to Cite

Shavazi Н., & Sirojiddinova Х. (2023). A NEW APPROACH TO THE TREATMENT OF RESPIRATORY DISEASES IN FREQUENTLY ILL CHILDREN. International Journal of Scientific Pediatrics, 2(1), 31–34. https://doi.org/10.56121/2181-2926-2023-2-1-31-34
Views: 64