INTEGRAL ASSESSMENT OF COMPENSATORY CAPABILITIES OF THE CARDIOVASCULAR SYSTEM IN CHILDREN WITH IRON DEFICIENCY ANEMIA
Abstract
Annotation. Relevance. Iron deficiency anemia (IDA) is still the most common pathology in the pediatric population. According to WHO, anemia affects more than 2 billion people in the world. The disease leads to delayed growth and development of children, reduced immunological resistance of the growing organism and functional disorders of internal organs. The negative influence of hemic hypoxia and sideropenia on the functional activity of the heart and vessels should be especially noted.
Objective. To study compensatory capabilities of the cardiovascular system in children suffering from IDA.
Material and methods. Physical performance was studied in 54 pediatric patients using the PWC 170 test, as well as echocardiographic examination at rest and during physical activity.
Results of the study and their discussion. The PWC 170 test showed that physical performance was reduced in children with IDA irrespective of the disease severity. The study of central hemodynamic parameters during moderate physical activity revealed a clear increase in all central hemodynamic parameters compared with baseline data. In patients with an average and severe degree of IDA both in conditions of muscular rest and at moderate physical load there is a significant increase of the basic hemodynamic parameters (minute blood flow and cardiac index) in comparison with the parameters of the control group children.
Conclusions. The above data indicate irrational expenditure of the heart functional reserves and decreased compensatory mechanisms of the cardiovascular system in patients with IDA.
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