THE EFFECT OF BREASTFEEDING AND SPECIALIZED THERAPEUTIC MIXTURES ON THE PHYSICAL DEVELOPMENT OF CHILDREN WITH CYSTIC FIBROSIS

Abstract

Cystic fibrosis (CF) is a progressive hereditary disease in which mainly the respiratory organs and the gastrointestinal tract, especially the pancreas, suffer. The purpose of the study. To evaluate the effect of the duration of breastfeeding and the use of specialized therapeutic mixtures on the physical development of children with cystic fibrosis. Materials and methods. The study included 127 children with a confirmed diagnosis of cystic fibrosis (CF) who received treatment and were monitored at the Republican Specialized Scientific and Practical Medical Center of the Ministry of Health of the Republic of Uzbekistan. Children with cystic fibrosis were divided into 2 groups: the main group and the comparison group. The main group consisted of 100 children whose studies were conducted before inclusion and 6 months after inclusion in the comprehensive treatment of SLS. The comparison group included 27 children with cystic fibrosis who did not receive SLS in complex treatment. Results. The results obtained indicate that breastfeeding also has a positive effect on the course of cystic fibrosis. For example, the duration of breastfeeding for the first 6 months and up to a year helps to reduce the frequency of exacerbation of the process in the lungs and gastrointestinal tract, which averaged 9.8±1.03 times (p<0.05) during the first 3 years of life, whereas with artificial feeding The number of exacerbations averaged 14.2±1.03. in order to achieve a greater effect of using SLS, the nature of feeding children in the first 2 years of life and the age of the child at the time of the intervention are important: breastfeeding from birth, up to 6 months and more, as well as the early onset of nutritional support using SLS, lead to higher chances of achieving normal physical development of children and the course of cystic fibrosis. Conclusions. The most effective strategy for managing children with cystic fibrosis is a combined approach that includes optimal duration of breastfeeding and timely administration of specialized therapeutic mixtures based on protein hydralizate in the presence of signs of EDD. This approach can significantly improve the nutritional status, slow the progression of complications, and improve the quality of life of patients with a life-threatening orphan hereditary genetic disease, such as cystic fibrosis.