OBSTRUKTIV BRONXIT BILAN OG'RIGAN BEMORLARDA HUJAYRA IMMUNITETINING HOLATI
Abstrakt
- Esanova Munira Ravshanovna
Izoh. Bolalardagi obstruktiv bronxit jiddiy tibbiy va ijtimoiy muammodir, chunki ular bolalar kasalliklarining sabablari orasida birinchi o'rinlardan birini egallaydi. Ko'pgina tadqiqotlarga qaramay, tez-tez kasal bo'lgan bolalarda obstruktiv bronxit muammosi to'liq hal qilinmayapti, bu o'z vaqtida tashxis qo'yish qiyinligi, klinik ko'rinishlarning o'ziga xos xususiyatlari va laboratoriya ma'lumotlari bilan bog'liq. Ilmiy tadqiqotning maqsadi obstruktiv bronxit bilan og'rigan bemorlarda hujayra immunitetining holatini o'rganishdir. Materiallar va tadqiqot usullari: hujayra immuniteti ko'rsatkichlari bilan bog'liqlikni o'rnatish uchun obstruktiv bronxit bilan og'rigan 80 nafar bemor 2 guruhga bo'lingan holda tekshirildi: I guruh - obstruktiv bronxit bilan 40 bemor, II guruh - tez-tez kasal bolalarda obstruktiv bronxit bilan og'rigan 40 bemor. Natijalar: Immunologik tadqiqot natijalari T-hujayra immunitetining buzilishini ko'rsatdi, bu CD3, CD4 ning pasayishi va CD8 ning pasayishi tendentsiyasi bilan namoyon bo'ldi, bu bemorlarda ikkilamchi immunitet tanqisligi holati mavjudligini ko'rsatadi, ehtimol tez-tez nafas olish kasalliklari. AOBda hujayra immunitetining patogenetik jihatdan noqulay o'sishi xavfining eng informatsion ko'rsatkichlari CD3+, CD4+, CD8+ subpopulyatsiyasining pasayishi hisoblanadi.
Xulosa. Ushbu tadqiqot bolalarda obstruktiv bronxit rivojlanishida immunitet holatining patogenetik rolini yaxshiroq tushunishga, klinik amaliyotda foydalanishga va kasallikning diagnostikasi, prognozi va davolashning yanada samarali usullarini ishlab chiqishga imkon beradi.
Kalit so'zlar:
Mualliflar haqida
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