AN INVESTIGATION OF THE RELATIONSHIP BETWEEN THE QUALITY OF LIFE OF THE CHILD PATIENT AND THE PARENT AFTER DESMOPRESSIN TREATMENT IN CHILDREN WITH PRIMARY NOCTURNAL ENURESIS

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Abstract

Our study aimed to assess the quality of life of both children with monosymptomatic enuresis and their parents during the enuresis period and through the process of cessation with desmopressin treatment. Materials and methods: The study assessed 78 children aged 6-18 with Monosymptomatic Nocturnal Enuresis (MEN) treated with desmopressin. Comprehensive evaluations, including physical exams and lab tests, were conducted. The surveys on the impact of enuresis on daily life and emotional well-being were evaluated. Results: The study observed 78 patients, averaging 10.6 years old, primarily treated for urinary incontinence with desmopressin. Patient demographics indicated 68% had education below high school, 74% were Turkish, and 26% Syrian. Familial data revealed an average of 3.87 siblings per patient. Key findings included a significant reduction in the number of incontinence days per week post-treatment (from 5.09 days to 2.59 days). Quality of Life (QOL) scores for both patients and parents showed significant improvement after treatment. The mean QOL for patients increased from 20 to 26.8, while for parents, it rose from 13 to 24.6. Overall, desmopressin demonstrated a positive impact on urinary incontinence and the associated quality of life. Conclusions: With treatment, there is a noticeable improvement in psychological, social, and emotional aspects among children with MEN and their parents. Therefore, it is essential to treat children experiencing MEN.

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List of references

Seibold J, Alloussi S, Todenhöfer T, Stenzl A, Schwentner C. [Primary monosymptomatic enuresis: diagnostics and therapy]. Urologe A 2013;52:9–10, 12–4. https://doi.org/10.1007/s00120-012-3074-4. DOI: https://doi.org/10.1007/s00120-012-3074-4

Nevéus T, von Gontard A, Hoebeke P, Hjälmås K, Bauer S, Bower W, et al. The standardization of terminology of lower urinary tract function in children and adolescents: report from the Standardisation Committee of the International Children’s Continence Society. J Urol 2006;176:314–24. https://doi.org/10.1016/S0022-5347(06)00305-3. DOI: https://doi.org/10.1016/S0022-5347(06)00305-3

Glazener CMA, Peto RE, Evans JHC. Effects of interventions for the treatment of nocturnal enuresis in children. Qual Saf Health Care 2003;12:390–4. https://doi.org/10.1136/qhc.12.5.390. DOI: https://doi.org/10.1136/qhc.12.5.390

Huang T, Shu X, Huang YS, Cheuk DK. Complementary and miscellaneous interventions for nocturnal enuresis in children. Cochrane Database Syst Rev 2011:CD005230. https://doi.org/10.1002/14651858.CD005230.pub2. DOI: https://doi.org/10.1002/14651858.CD005230.pub2

Monda JM, Husmann DA. Primary nocturnal enuresis: a comparison among observation, imipramine, desmopressin acetate and bed-wetting alarm systems. J Urol 1995;154:745–8. DOI: https://doi.org/10.1016/S0022-5347(01)67152-0

Harari MD. Nocturnal enuresis. J Paediatr Child Health 2013;49:264–71. https://doi.org/10.1111/j.1440-1754.2012.02506.x. DOI: https://doi.org/10.1111/j.1440-1754.2012.02506.x

Ferrara P, Romano V, Cortina I, Ianniello F, Fabrizio GC, Chiaretti A. Oral desmopressin lyophilisate (MELT) for monosymptomatic enuresis: structured versus abrupt withdrawal. J Pediatr Urol 2014;10:52–5. https://doi.org/10.1016/j.jpurol.2013.05.021. DOI: https://doi.org/10.1016/j.jpurol.2013.05.021

Bastiaansen D, Koot HM, Ferdinand RF, Verhulst FC. Quality of life in children with psychiatric disorders: self-, parent, and clinician report. J Am Acad Child Adolesc Psychiatry 2004;43:221–30. https://doi.org/10.1097/00004583-200402000-00019. DOI: https://doi.org/10.1097/00004583-200402000-00019

M. J.Morison. Living with a young person who wets the bed:the families experience. British Journal of Nursing 2000:9:572-78. DOI: https://doi.org/10.12968/bjon.2000.9.9.6294

Butler RJ, Brewin CR, Forsythe WI. Maternal attributions and tolerance for nocturnal enuresis. Behav Res Ther 1986;24:307–12. https://doi.org/10.1016/0005-7967(86)90190-7. DOI: https://doi.org/10.1016/0005-7967(86)90190-7

Liu X, Sun Z, Uchiyama M, Li Y, Okawa M. Attaining nocturnal urinary control, nocturnal enuresis, and behavioral problems in Chinese children aged 6 through 16 years. J Am Acad Child Adolesc Psychiatry 2000;39:1557–64. https://doi.org/10.1097/00004583-200012000-00020. DOI: https://doi.org/10.1097/00004583-200012000-00020

Development of the World Health Organization WHOQOL-BREF quality of life assessment. The WHOQOL Group. Psychol Med 1998;28:551–8. https://doi.org/10.1017/s0033291798006667. DOI: https://doi.org/10.1017/S0033291798006667

Safarinejad MR. Prevalence of nocturnal enuresis, risk factors, associated familial factors and urinary pathology among school children in Iran. J Pediatr Urol 2007;3:443–52. https://doi.org/10.1016/j.jpurol.2007.06.001. DOI: https://doi.org/10.1016/j.jpurol.2007.06.001

Meydan EA, Civilibal M, Elevli M, Duru NS, Civilibal N. The quality of life of mothers of children with monosymptomatic enuresis nocturna. Int Urol Nephrol 2012;44:655–9. https://doi.org/10.1007/s11255-011-0087-7. DOI: https://doi.org/10.1007/s11255-011-0087-7

Naitoh Y, Kawauchi A, Soh J, Kamoi K, Miki T. Health related quality of life for monosymptomatic enuretic children and their mothers. J Urol 2012;188:1910–4. https://doi.org/10.1016/j.juro.2012.07.012. DOI: https://doi.org/10.1016/j.juro.2012.07.012

EA Akil I, Canda E, Ozyurt BC, Eser E. An evaluation of quality of life of mothers of children with enuresis nocturna. Pediatr Nephrol 2008:23(1):93-8. https://doi.org/10.1007/s00467-007-0605-0. DOI: https://doi.org/10.1007/s00467-007-0605-0

Üçer O, Gümüş B. Quantifying subjective assessment of sleep quality, quality of life and depressed mood in children with enuresis. World J Urol 2014;32:239–43. https://doi.org/10.1007/s00345-013-1193-1. DOI: https://doi.org/10.1007/s00345-013-1193-1

How to Cite

Suleyman , S. (2023). AN INVESTIGATION OF THE RELATIONSHIP BETWEEN THE QUALITY OF LIFE OF THE CHILD PATIENT AND THE PARENT AFTER DESMOPRESSIN TREATMENT IN CHILDREN WITH PRIMARY NOCTURNAL ENURESIS. International Journal of Scientific Pediatrics, 2(6), 217–222. https://doi.org/10.56121/2181-2926-2023-2-6-217-222
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