PREDICTORS OF THE DEVELOPMENT OF RECURRENT BRONCHIAL OBSTRUCTION IN CHILDREN

Abstract

Abstract. Purpose of the study: to determine the significance of risk factors for the development of recurrent bronchial obstruction in children. Material and methods of research. A total of 240 children were examined and divided into 3 groups: Group I - patients with acute obstructive bronchitis (AOB), acute bronchiolitis (ABL), Group II - children with recurrent obstructive bronchitis (ROB) and bronchial asthma (BA), Group III - patients with acute bronchitis without bronchial obstruction (BA). To assess the significance of risk factors for the development of recurrent and relapsing course of BOS, we analysed genealogical, biological and social anamnesis, premorbid and family background, in children of the studied groups, characterising the state of family health and features of child development in the ante- and postnatal periods, as well as in the first years of the child's life. Results of the study and discussion. When studying the causes and factors influencing the development and course of BOS in children, the most important is the study of background diseases that aggravate and prolong the course of bronchial obstruction. The study of pre-mobilisation background in patients of the compared groups showed that a number of factors were significantly more frequent in patients with acute and recurrent course of bronchobstructive syndrome. Conclusions. It was found that the risk factors for the development of recurrent course of bronchial obstruction in children are: artificial feeding (P<0.002; OR=4.80), rickets (P<0.02; OR=2.15), overweight (P<0.002; OR=5.40), atopy (P<0.001; OR=18.32), first episode of BOS before the age of 1 year (P<0.002; OR=3.01), absence of fever (P<0.002; OR=12.95) and catarrhal syndrome (P<0.001; OR=60.0) during the episode of illness.