CATAMNESTIC OBSERVATION OF THE EFFECTIVENESS OF IMMUNOCORRECTIVE THERAPY IN CHILDREN WHO ARE OFTEN ILL
Abstract
The article presents data on the study of the effectiveness of long-term anti-relapse therapy in frequently ill children based on the complex use of the immunocorrecting drug Broncho-munal and the adjuvant sodium Nucleinate. To fulfill the tasks set, the anti-relapse efficacy was determined by three parameters out of 146 in 46 frequently ill children (CBD): the incidence rate, the frequency of recurrent respiratory infections (RRI) and the lengthening of remission periods. The study of the frequency, multiplicity and timing of remissions of respiratory tract diseases in CBD with different methods of treatment indicates the feasibility of immunocorrecting therapy with the combined use of Bronchomunal and sodium Nucleinate. An increase in the frequency of the disease is the basis for repeated use of immunocorrective drugs.
About the Authors
List of references
Romantsov M.G., Melnikova I.Yu. Frequently ill children: an urgent problem of pediatrics. The successes of modern natural science 2014:16–8.
Nuriddinovna SK, Mustafayevna NS, Tursunbayevna ON. Intrauterine infection as a developmental factor perinatal pathology. 1 2021;2:107–11. https://doi.org/10.47494/cajmns.v2i1.85.
Sirojiddinova X.N., Usmanova M.F., Ortikboyeva N.T., Tuxtayeva M.M. Immunological dynamics of recurrent respiratory infections in frequently sick children on the background of immunocorrective therapy. IJIEMR Transactions 2021;10:131–4.
SXN Ortikboyeva NT, Aminova NA, Akmaljanova AA. Peculiarities of neurosonography in hypoxic-ischemic encephalopathy in newborns with intrauterine infection. Eurasian journal of academic research 2021;1:261–5.
G.A S. The problem of frequently ill children in pediatrics. Pediatrics The Magazine Named after G N Speransky 2015;94:167–9.
Sapozhnikov V.G. Selected chapters of childhood diseases. Monograph. 4th edition, expanded Tula: Polygraphinvest 2016:298.
Nuriddinova S, Kizi I, Mustafayevna N, Tursunbayevna O, Dilshodbekovna A. Metabolic Changes Following Post-Hypoxic Complications in Newborns. International Journal of Current Research and Review 2020;12:173–7. https://doi.org/10.31782/IJCRR.2020.122229.
Shamsiev F.M., Musajanova R.A. Mirsalikhova N.H. Azizova N.D., Karimova N.I. Uzakova G.B. Immunocorrective therapy of children with recurrent obstructive bronchitis and bronchial asthma. Pediatrics 2017:106–10.
Tukhtaeva M.M., Usmanova M.F., Omonova G.Z., Ochilova B.S. Psychomotor changes in hypoxic lesions of the central nervous system in newborns. Eurasian journal of academic research 2021;1:271–5.
Tukhtaeva M.M., Abduxalik-Zade G.A., Burxonova D.B., Mirkomilova G.M. Clinic - anamnestic characteristic of hypoxic-ischemic encephalopathy in newborns. Eurasian journal of academic research 2021;1:261–5.
Sirozhiddinova H.N. Abdullayeva M.N. Monograph. Optimization of the treatment of respiratory pathology in frequently ill children. Самарканд 2021:120.
Toivonen L, Karppinen S, Schuez-Havupalo L, Teros-Jaakkola T, Vuononvirta J, Mertsola J, et al. Burden of Recurrent Respiratory Tract Infections in Children: A Prospective Cohort Study. Pediatr Infect Dis J 2016;35:e362–9. https://doi.org/10.1097/INF.0000000000001304.
Shabalov N.P. Neonatology. M: MED press-inform 2009:138–98.
Kallen AJ, Reed C, Patton M, Arnold KE, Finelli L, Hageman J. Staphylococcus aureus community-onset pneumonia in patients admitted to children’s hospitals during autumn and winter of 2006-2007. Epidemiol Infect 2010;138:666–72. https://doi.org/10.1017/S095026880999135X.
How to Cite
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
