BOLALARDA SURUNKALI BUYRAK KASALLIGI RIVOJLANIShINING IMMUNPATOGENETIK XUSUSIYATLARI
Abstrakt
Bolalardagi me'yoriy va patologik jarayonlarda, xususan surunkali buyrak kasalligi immunpatogenetik rivojlanishida sitokin profili boshqaruvi ahamiyatini aniqlash. Xulosa: sitokin mediatorlarining turli xil xususiyatlari organizmni yuqumli agentlardan himoya qilish va to‘qimalarni tiklashga xizmat qiladi. Birinchi navbatda, sitokinlar mahalliy himoya jarayonlarining rivojlanishini tartibga soladi, yallig‘lanish reaksiyasining shakllanishini sodir etadi. Shuning uchun ham yallig‘lanishni qo‘llovchi va yallig‘lanishga qarshi sitokinlarning tarkibi va ularning nisbatini yallig‘lanish jarayoni va fibrozning kuchayishini eng ob'ektiv ko‘rsatkichlari deb hisoblash mumkin. Sitokin tizimidagi nomutanosiblikni bashorat qilish, surunkali buyrak kasalligining biomarkeri sifatida, kasallikni kechishi va davolash samaradorligini baholashda qo‘llanilishi mumkin. Adabiyot ma'lumotlarini tahlil qilish surunkali buyrak kasalliklarida sitokin holatini o‘rganishning ilmiy va amaliy ahamiyatini yoritib berdi.
Kalit so'zlar:
Mualliflar haqida
Adabiyotlar ro'yxati
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