BOLALARDA MIKOPLAZMA PNEVMONIYASI KLINIK-DIAGNOSTIK MIZONLARINI XUSUSIYATLARI
Abstrakt
Annotatsiya. Ilmiy tadqiqotlarga qaramay, etiologik omilni erta tashxislashning murakkabligi, kasallikning klinik va laboratoriya ko'rinishlarining o'ziga xos xususiyatlari tufayli bolalarda atipik pnevmoniya muammosi hal etilmagan. Atipik pnevmoniyaning etiologik omilini o'z vaqtida aniqlash ko'p jihatdan antibiotik terapiyasining samaradorligini aniqlaydi, bu kasallikning kechishi va natijasiga keskin ta'sir qiladi va madaniy tashxis qo'yish qiyin, chunki mikoplazma hujayra ichidagi patogen bo'lib, hatto smear mikroskopida ham aniqlanmaydi. Turli xil yallig'lanish kasalliklari patogenezini o'rganishning hozirgi yo'nalishlaridan biri organizmning infektsiyaga reaktsiyasining sezgir va o'ziga xos biomarkerlari bo'lgan yallig'lanishga qarshi va yallig'lanishga qarshi sitokinlarning holatini aniqlashdir. Pediatrik amaliyotda sitokin profil ko'rsatkichlarining variantlari va ularning bolalardagi pnevmoniya kursi bilan aloqasi faqat ko'rsatkichdir. Tadqiqotning maqsadi bolalarda mikoplazmal pnevmoniyaning klinik diagnostik mezonlarini o'rganish edi.
Materiallar va tadqiqot usullari. Biz 60 nafar bemorni tekshirdik, ularda kasallikning etiologik omiliga qarab, jamiyat tomonidan orttirilgan pnevmoniya bilan og'rigan bemorlar 2 guruhga bo'lingan: I guruh - mikoplazmal etiologiyali 30 bemor, II guruh - tipik etiologiyali pnevmoniya bilan og'rigan 30 bemor. Tadqiqotlar natijalari shuni ko'rsatdiki, mikoplazmal pnevmoniya bilan kasallangan bolalarda immunologik buzilishlar standart qiymatlarga nisbatan yallig'lanishga qarshi va yallig'lanishga qarshi sitokinlarning sezilarli darajada oshishi bilan tavsiflanadi.
Kalit so'zlar:
Mualliflar haqida
Adabiyotlar ro'yxati
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