GENTAMITSINNI KALAMUSHLARGA LIMFOTROPIK PRETRAXEAL VA MUSHAK ORASIGA YUBORIB FARMAKOKINETIKASINI O’RGANISH
Abstrakt
Maqola limfotrop pretraxeal va mushak ichiga yuborish usullari bilan kalamushlarda gentamitsinning farmakokinetikasini eksperimental o'rganishga bag'ishlangan. Kalamushlarning qonida va nafas olish organlarining to'qimalarida antibiotikning kontsentratsiyasi dinamikasi bo'yicha ma'lumotlar berilgan, limfotrop pretrakeal yuborish usuli mushak ichiga nisbatan antibiotikning yuqori konsentratsiyasini ta'minlashi ko'rsatilgan. Ushbu usulning yuqori terapevtik samaradorligiga limfa tizimi, shuningdek, organlar va to'qimalar o'rtasidagi aloqalar mavjudligi tufayli erishish mumkin. Bu holat sizga preparatni bevosita zararlangan organga etkazish imkonini beradi. Bundan tashqari, diqqat markazida limfotropik terapiya bo'lsa, preparatning optimal kontsentratsiyasi 24 soat davomida saqlanadi. Shuning uchun preparatni tez-tez qabul qilishning hojati yo'q (masalan, antibiotik terapiyasi bilan), siz dorilarning kursini va kunlik dozalarini kamaytirishingiz mumkin. Limfotropik tarzda yuboriladigan preparat ichaklarga, buyraklarga, jigarga toksik ta'sir ko'rsatishga qodir emas, chunki preparatning faqat kichik bir qismi qon oqimiga kiradi.
Kalit so'zlar:
Mualliflar haqida
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