THE CHARACTERISTIC OF THE IMMUNE STATUS AT HIV-INFECTED CHILDREN WITH ACUTE RHINOSINUSITIS
Abstract
The immune status has been studied at 35 HIV-infected of children with ARS. The control group of comparison consisted from 14 practically healthy faces. At a HIV-infected of patients with ARS has revealed deep infringements of the immune status, especially from the T-link of immunity and its subpopulations, and also frustration humoral an immunity link, suppression of proinflammatory cytokine IL-10 and increase proinflammatory IFN-γ. Under the influence of the spent treatment have not revealed certain changes from the immune status at patients. It is possible to ascertain only positive changes of maintenance IL-10 and parallel decrease IFN-γ in dynamics of treatment. In the main group there were 25 HIV-infected patients with ARS, and in the control group there were 14 practically healthy children of the same age who did not have a history of ARS and HIV. All 35 HIV-infected children were registered with the Bukhara Regional AIDS Center. Patients received antiretroviral therapy, antibacterial, anti-inflammatory and local therapy in a hospital setting.
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